The Diocese of Wheeling-Charleston has long supported the needs of Catholic students at Shepherd University.
In 2004, Catholic Campus Ministry was officially formed as a student group on campus. Mass was held on campus about once a month. Students often participated in the life of the area parishes. In 2006, the Diocese of Wheeling Charleston decided to hire a part-time campus minister to serve the needs of the students. Finally in 2008, the Good Shepherd Catholic Campus Ministry Center was blessed and dedicated. The Center allows students an opportunity for fellowship and outreach, as well as a weekly place for Liturgy.